|Western Blot (WB)||1:250|
|Tested Species reactivity||Mouse|
|Host / Isotype||Mouse / IgG|
|Immunogen||Mouse Mist1, N-terminus residues 1-20.|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-518 detects Mist1 from mouse samples. MA1-518 has been successfully used in Western blot. By Western blot, MA1-518 detects a ~29 kDa band representing Mist1. The MA1-518 immunogen is mouse Mist1, N-terminus residues 1-20.
Mist 1 plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. This protein also negatively regulates bHLH-mediated transcription through an N-terminal repressor domain, and serves as a key regulator of acinar cell function, stability, and identity.
Mist 1 is also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport, and may function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1810009C13Rik; basic helix-loop-helix domain containing, class B, 8; bHLHa15; Bhlhb8; Class A basic helix-loop-helix protein 15; Class B basic helix-loop-helix protein 8; MIST-1; Mist1; Muscle, intestine and stomach expression 1
Gene Aliases: 1810009C13Rik; Bhlha15; Bhlhb8; MIST-1; Mist1
UniProt ID: (Mouse) Q9QYC3
Entrez Gene ID: (Mouse) 17341
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