|Western Blot (WB)||1:1000|
|Tested Species reactivity||Bovine, Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the amino-terminal residues of human Mst4|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with Mst1-3.
The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mammalian STE20-like protein kinase 4; mammalian sterile 20-like 4; MST-4; MST3 and SOK1-related kinase; mst4; OTTHUMP00000215132; OTTHUMP00000215134; serine/threonine protein kinase MASK; serine/threonine protein kinase MST4; Serine/threonine-protein kinase 26; Serine/threonine-protein kinase MASK; Serine/threonine-protein kinase MST4; STE20-like kinase 4; STE20-like kinase MST4
Gene Aliases: 2610018G03Rik; BOS_25203; MASK; MST4; RGD1563568; STK26
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