|Western Blot (WB)||1:10000|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Human Mus81 from Sp2/0 Ag.14 cells|
|Contains||0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
MA1-5837 detects Mus81 in human samples.
MA1-5837 has been successfully used in Western blot and immunoprecipitation procedures.
The MA1-5837 immunogen is human Mus81.
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Crossover junction endonuclease MUS81; FLJ21012; FLJ44872 MUS81; MUS81 endonuclease homolog; SLX3 structure-specific endonuclease subunit homolog
Gene Aliases: MUS81; SLX3
UniProt ID: (Human) Q96NY9
Entrez Gene ID: (Human) 80198
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