|Tested Species reactivity||Bacteria|
|Host / Isotype||Rabbit / IgG|
|Storage buffer||PBS, pH 7.2, with 10mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-28997 detects Mycobacterium tuberculosis from bacteria samples.
PA1-28997 has been successfully used in ELISA and immunohistochemistry (frozen tissue) applications.
The PA1-28997 immunogen is: Purified PPD.
Tuberculosis is a chronic bacterial infection which remains one of the leading killers of young adults world wide. Mycobacterium tuberculosis enters the alveoli by airborne transmission. They are engulfed by alveolar macrophages but resist destruction. Although the exact mechanism is not known, it is suspected that that Mycrobacterium tuberculosis survives by preventing the fusion of the phagosome and lysosome. As the bacterium accumulates it forms a tubercle, spreads to the lymph nodes and becomes a systemic infection. Although treatments for tuberculosis do exist, new strains of Mycobacterium tuberculosis that appear to have multiple-drug resistance (MDR) pose a considerable threat to public health.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: M. tuberculosis; myobacter
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