|Immunohistochemistry (Paraffin) (IHC (P))||1:500-1:1000|
|Immunocytochemistry (ICC)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Rabbit muscle myosin|
|Contains||<0.1% sodium azide|
|Storage conditions||4° C|
MA5-11748 targets Myosin Skeletal Muscle in IHC (P) applications and shows reactivity with Human samples.
The MA5-11748 immunogen is rabbit muscle myosin.
Myosin is a 480kDa protein known to interact with actin in muscle and in non-muscle cells. It contains two identical heavy chains (200kDa each) and four light chains (15-26kDa). Myosin molecules consist of two major regions: tails (rod) and heads; they aggregate into filaments through the tail region and interact with actin and with ATP through the head region. Multiple forms of myosin heavy chains exist for each muscle type-skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle. These are designated at type I (slow-twitch) and type II (fast-twitch).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adult; adult 1; epididymis luminal protein 71; heavy polypeptide 1; MyHC-2x; MyHC-IIx/d; myosin; myosin heavy chain; Myosin heavy chain 1; Myosin heavy chain 2x; Myosin heavy chain IIx/d; Myosin heavy chain, skeletal muscle, adult 1; myosin, heavy chain 1, skeletal muscle, adult; myosin, heavy polypeptide 1, skeletal muscle, adult; Myosin-1; skeletal muscle
Gene Aliases: HEL71; MYH1; MYHa; MyHC-2x; MyHC-2X/D; MYHSA1
UniProt ID: (Human) P12882
Entrez Gene ID: (Human) 4619
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