|Immunohistochemistry (Paraffin, Frozen) (IHC (P, F))||5-10 µg/ml|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||5-10 µg/ml|
|Tested Species reactivity||Bovine, Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues R(808) M D E R P I H A E P Q Y P V R S A A P(827) of human N-Cadherin.|
|Storage buffer||PBS, pH 7.4|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-20359 detects N-Cadherin in human, mouse, and bovine samples. This antibody does not cross-react with E or P Cadherin.
PA1-20359 has been successfully used in immunohistochemistry (frozen and FFPE) and Western blot procedures.
The PA1-20359 immunogen is a synthetic peptide corresponding to residues R(808) M D E R P I H A E P Q Y P V R S A A P(827) of human N-Cadherin.
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cadherin 2, type 1, N-cadherin (neuronal); Cadherin-2; calcium-dependent adhesion protein, neuronal; CD325; CDHN; CDw325; CDw325 antigen; N-cadherin 1; NCAD; Neural cadherin
Gene Aliases: BOS_22126; CD325; CDH2; CDHN; CDw325; N-cadherin; NCAD
Molecular Function: cadherin
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