|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 111 of Human NADE|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27690 targets NADE in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27690 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 111 of Human NADE.
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bex; BEX3; brain expressed; Brain-expressed X-linked protein 3; DXS6984E; HGR74; NADE; nerve growth factor receptor (TNFRSF16) associated protein 1; Nerve growth factor receptor-associated protein 1; Ovarian granulosa cell 13.0 kDa protein HGR74; ovarian granulosa cell protein (13kD); p75NTR-associated cell death executor; Protein BEX3; X-linked 3
Gene Aliases: Bex; BEX3; DXS6984E; HGR74; NADE; NGFRAP1
UniProt ID: (Human) Q00994
Entrez Gene ID: (Human) 27018
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