|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the C-terminal region of human NBL1|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
This gene product is the founding member of the evolutionarily conserved CAN family of proteins, which contain a domain resembling the CTCK motif found in a number of signaling molecules. These proteins are secreted, and act as BMP antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: D1S1733E; DAN; DAN domain family member 1; DAND1; differential screening-selected gene aberrant in neuroblastoma; NB; neuroblastoma; neuroblastoma candidate region suppression of tumorigenicity 1; neuroblastoma candidate region, suppression of tumorigenicity 1; neuroblastoma suppression of tumorigenicity 1; NO3
Gene Aliases: D1S1733E; DAN; DAND1; NB; NO3
Entrez Gene ID: (Human) 4681
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