|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 451 and 668 of Human NCKIPSD|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30625 targets NCKIPSD in WB applications and shows reactivity with Human samples.
The PA5-30625 immunogen is recombinant fragment corresponding to a region within amino acids 451 and 668 of Human NCKIPSD.
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 54 kDa VacA-interacting protein; 54 kDa vimentin-interacting protein; 90 kDa; 90 kDa SH3 protein interacting with Nck; AF3P21; dia interacting protein; Dia-interacting protein 1; diaphanous protein interacting protein; Diaphanous protein-interacting protein; DIP-1; DIP1; NCK-interacting protein with SH3 domain; ORF1; SH3 adapter protein SPIN90; SH3 protein interacting with Nck; SH3 protein interacting with Nck, 90 kDa; SPIN90; VIP54; WASLBP; WASP-interacting SH3-domain; WASP-interacting SH3-domain protein; WISH; Wiskott-Aldrich syndrome protein-interacting protein
Gene Aliases: AF3P21; DIP; DIP1; NCKIPSD; ORF1; SPIN90; VIP54; WASLBP; WISH
UniProt ID: (Human) Q9NZQ3
Entrez Gene ID: (Human) 51517
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