|Western Blot (WB)||1:500|
|Tested Species reactivity||Mouse|
|Host / Isotype||Armenian hamster / IgG2b|
|Immunogen||N-terminal peptide of murine Ndfip 1 coupled to KLH (VEPACGSGYQQLQNEEPGE)|
|Contains||0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
MA5-18029 targets NDFIP1 in ELISA and WB applications and shows reactivity with Mouse samples.
The MA5-18029 immunogen is n-terminal peptide of mouse Ndfip 1 coupled to KLH (VEPACGSGYQQLQNEEPGE).
The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: N4WBP5; NDFIP1; NEDD4 family-interacting protein 1; Nedd4 WW binding protein 5; NEDD4 WW domain-binding protein 5; Nedd4 WW-binding protein 5
Gene Aliases: 0610010M22Rik; N4wbp5; Ndfip1
UniProt ID: (Mouse) Q8R0W6
Entrez Gene ID: (Mouse) 65113
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