|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 130 and 410 of Human NFKBIL2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31338 targets NFKBIL2 in WB applications and shows reactivity with Human samples.
The PA5-31338 immunogen is recombinant fragment corresponding to a region within amino acids 130 and 410 of Human NFKBIL2.
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: I-kappa-B-related protein; ikappaBR; IKBR; Inhibitor of kappa B-related protein; NF-kappa-B inhibitor-like protein 2; NFKBIL2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2; Tonsoku-like protein
Gene Aliases: IKBR; NFKBIL2; TONSL
UniProt ID: (Human) Q96HA7
Entrez Gene ID: (Human) 4796
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