|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 45 of NKG2-C|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28837 targets NKG2-C in WB applications and shows reactivity with Human samples.
The PA5-28837 immunogen is a synthetic peptide corresponding to a region within amino acids 1 and 45 of NKG2-C.
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD159 antigen-like family member C; CD159c; killer cell lectin-like receptor subfamily C, member 2; KLRC2; NK cell receptor C; NKG2-C; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor; NKG2C
Gene Aliases: CD159c; KLRC2; NKG2-C; NKG2C
UniProt ID: (Human) P26717
Entrez Gene ID: (Human) 3822
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