|Immunohistochemistry (Paraffin) (IHC (P))||9 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 19 amino acid peptide from C-terminus of human NMBR.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Marmoset, Mouse, Elephant, Bovine (89%) Rat, Panda, Dog, Bat, Rabbit, Pig, Platypus (84%).
The neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bombesin BB1 receptor; bombesin receptor 1; epididymis secretory sperm binding protein Li 185a; Epididymis tissue protein Li 185a; Neuromedin B receptor; Neuromedin-B receptor; Neuromedin-B-preferring bombesin receptor; NMB-preferring receptor; NMB-R; NMBR
Gene Aliases: BB1; BB1R; NMB-R; NMBR
UniProt ID: (Human) P28336
Entrez Gene ID: (Human) 4829
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