|Western Blot (WB)||1:100-1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 125-140 (PHSLHPARDLQSHRPA) of human Nod2.|
|Storage buffer||whole serum with glycerol|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Apaf-1 and Nod1 are members of a protein family, each of which contains a caspase recruitment domain (CARD) linked to a nucleotide-binding domain, which regulate apoptosis and/or NF-kB activation. Recently, Nod2, a third member of the family has been identified. Recent studies indicate that Nod2 activates NF-kB, but unlike Nod1, this new homologue is primary expressed in monocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACUG; BLAU; CARD domain containing 2; CARD15; caspase recruitment domain family; caspase recruitment domain family, member 15; caspase recruitment domain protein 15; Caspase recruitment domain-containing protein 15; CD; CLR16.3; IBD1; Inflammatory bowel disease protein 1; leucine rich repeat and CARD domain containing 2; member 15; NLR family; NLR family, CARD domain containing 2; NLRC2; NOD-like receptor C2; NOD2B; nucleotide-binding oligomerization domain; nucleotide-binding oligomerization domain 2; nucleotide-binding oligomerization domain containing 2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2; Nucleotide-binding oligomerization domain-containing protein 2; PSORAS1
Gene Aliases: ACUG; BLAU; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2; NOD2B; PSORAS1
UniProt ID: (Human) Q9HC29
Entrez Gene ID: (Human) 64127
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