|Western Blot (WB)||1:1,000|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the N-terminal residues M(1) P G R K A R R N A P V N P T R(16) of mouse Noxa.|
|Storage buffer||whole serum|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-18331 detects Noxa from mouse samples.
PA1-18331 has been successfully used in Western blot procedures.
The PA1-18331 immunogen is a synthetic peptide corresponding to the N-terminal residues M(1) P G R K A R R N A P V N P T R(16) of mouse Noxa, conjugated to diphtheria toxoid.
Reconstitute with 100 ul of distilled water.
The Bcl-2 family of proteins which regulate apoptosis share identical sequences called Bcl-2 Homology domains (BH1-4). The BH3 proteins, including BID, NOXA, PUMA, BIK, BIM and BAD are all pro-apoptotic and share sequence identity within the amphipathic alpha-helical BH3 region, which is essential for their apoptotic function. NOXA is highly expressed in adult T-cell leukemia cell line.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adult T cell leukemia-derived PMA-responsive; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMAIP1; Protein Noxa
Gene Aliases: Noxa; Pmaip1
UniProt ID: (Mouse) Q9JM54
Entrez Gene ID: (Mouse) 58801
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