|Immunohistochemistry (Paraffin) (IHC (P))||11 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from C-terminus of human DAX1.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Orangutan, Monkey (100%) Gorilla (95%) Gibbon (90%) Marmoset (85%).
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adrenal hypoplasia congenita; AHC; AHCH; AHX; DAX 1; DAX-1; Dax-1 receptor; DAX1; Dosage-sensitive sex reversal; DSS; DSS-AHC critical region on the X chromosome protein 1; GTD; HHG; NR0B1; NROB1; Nuclear hormone receptor; Nuclear receptor DAX-1; Nuclear receptor DAX1; Nuclear receptor subfamily 0 group B member 1; nuclear receptor subfamily 0, group B, member 1; SRXY2
Gene Aliases: AHC; AHCH; AHX; DAX-1; DAX1; DSS; GTD; HHG; NR0B1; NROB1; SRXY2
UniProt ID: (Human) P51843
Entrez Gene ID: (Human) 190
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