|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 438-466 amino acids from the C-terminal region of human NR2C2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse and rat based on sequence homology.
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C-terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes.
Protein Aliases: NR2C2; Nuclear hormone receptor TR4; Nuclear receptor subfamily 2 group C member 2; nuclear receptor subfamily 2, group C, member 2; Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; orphan receptor TR4; TAK1; testicular nuclear receptor 4; Testicular receptor 4; TR4
Gene Aliases: NR2C2; TAK1; TR4
UniProt ID: (Human) P49116
Entrez Gene ID: (Human) 7182