|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 72 and 293 of Human NSDHL|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30577 targets NSDHL in WB applications and shows reactivity with Human samples.
The PA5-30577 immunogen is recombinant protein fragment corresponding to a region within amino acids 72 and 293 of Human NSDHL.
The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: decarboxylating; H105E3; member 1; Protein H105e3; SDR31E1; short chain dehydrogenase/reductase family 31E; short chain dehydrogenase/reductase family 31E, member 1; sterol-4-alpha-carboxylate 3-dehydrogenase; Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; XAP104
Gene Aliases: H105E3; NSDHL; SDR31E1; XAP104
UniProt ID: (Human) Q15738
Entrez Gene ID: (Human) 50814
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