|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human NXPH4|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
Members of the Neurexophilin family are neuropeptide-like glycoproteins that undergo proteolytic processing after synthesis. As secreted proteins, Neurexophilins are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I-alpha (a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. Neurexophilins contain five common domains including a variable N-terminal domain, a highly conserved N-glycosylated central domain, a short linker region and a cysteine-rich conserved C-terminal domain. Neurexophilin-4, also known as NXPH4 or NPH4, is a 308 amino acid secreted protein belonging to the neurexophilin family. Neurexophilin-4 is expressed in brain, spleen and testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alternative protein NXPH4; Neurexophilin 4; Neurexophilin-4; NPH4; NXPH4; UNQ1928/PRO4403
Gene Aliases: NPH4; NXPH4; UNQ1928/PRO4403
Molecular Function: signaling molecule
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