|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||1:1,000,000|
|Tested Species reactivity||Bovine, Human, Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Purified axonal form of bovine NF-H.|
|Contains||10mM sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody reacts primarily with the phosphorylated axonal form of NF-H and shows some cross-reactivity with phosphorylated NF-M, which has similar phosphorylation sites to NF-H.
Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (~70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 200 kDa neurofilament protein; neurofilament 200kDa; Neurofilament heavy polypeptide; Neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; NF 200 kD; NF-H; NFH; NHC
Gene Aliases: CMT2CC; KIAA0845; mKIAA0845; NEFH; NF-H; NF200; NFH
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