|Immunohistochemistry (Frozen) (IHC (F))||1:25-1:200|
|Immunohistochemistry (Paraffin) (IHC (P))||1:25-1:200|
|Western Blot (WB)||1:100-1:1000|
|Immunohistochemistry (IHC)||See 5 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Avian , Rabbit Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human neurofilament preparation|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
MA1-06803 detects neurofilament 70 kDa in human samples.
MA1-06803 has sucessfully been used in Western blotting, and immunohistochemistry procedures. By Western blot it detects a 70 kDa band representing neurofilament ~70 kDa.
The MA1-06803 immunogen is a human neurofilament preparation.
Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (~70, 160, and 200 kDa) occur in both the central and
peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 68 kDa neurofilament protein; 70 kDa neurofilament protein; CMT1F; CMT2E; light molecular weight neurofilament protein; Neurofilament light polypeptide; neurofilament protein, light chain; neurofilament subunit NF-L; Neurofilament triplet L pro; Neurofilament triplet L protein; neurofilament, light polypeptide 68kDa; NF-L; NFL; NLC; protein phosphatase 1, regulatory subunit 110
Gene Aliases: CMT1F; CMT2E; NEFL; NF-L; NF68; NFL; PPP1R110
UniProt ID: (Human) P07196
Entrez Gene ID: (Human) 4747
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