|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 242-272 amino acids from the C-terminal region of human Neurogenin2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells. In the course of mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia and that Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATOH4; atonal homolog 4; bHLHa8; Class A basic helix-loop-helix protein 8; Helix-loop-helix protein mATH-4A; mATH4A; NEUROG2; Neurogenin-2; NGN-2; NGN2; Protein atonal homolog 4
Gene Aliases: Ath4a; ATOH4; BHLHA8; Math4A; NEUROG2; ngn-2; NGN2
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