|ELISA (ELISA)||Assay Dependent|
|Flow Cytometry (Flow)||3-5 µg/10^6 cells|
|Immunocytochemistry (ICC)||2 µg/ml|
|Immunofluorescence (IF)||2 µg/ml|
|Western Blot (WB)||2 µg/ml|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human, Insect, Mouse, Rat|
|Published species reactivity||Mammal|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Synthetic peptide derived from an internal sequence of the human, mouse, and rat NK1 receptor proteins|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
Tachykinin Receptor 1, a member of the Tachykinin Receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two variants of the tachykinin receptor 1 are produced by alternative splicing. Tachykinin receptor 1 has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Neurokinin 1 receptor; Neurokinin receptor 1; NK-1 receptor; NK-1R; Nk1 receptor; Nk1 tachykinin receptor; NK1R; NKIR; SPR; substance P receptor; Substance-P receptor; TAC1R; Tachykinin 1 receptor; Tachykinin receptor 1; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor); TACR1
Gene Aliases: NK1R; NKIR; SPR; TAC1R; TACR1
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