|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Western Blot (WB)||1-3 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Tested Species reactivity||Human, Non-human primate|
|Published species reactivity||Sheep|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 350-400 of human NPY2-R.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
NPY2R is also expected to react with mouse and canine samples based on sequence homology.
Suggested positive control: human kidney protein, kidney lysate.
NPY2 receptor is a member of GPCR1 family and is localized primarily on Neuropeptide Y-expressing neurons in the hypothalamic region of the brain. It binds specifically to the C-terminal of Neuropeptide Y and is responsible for regulation of presynaptic relase of noradrenaline. Reports suggest a probable role of NPY2 receptor in regulation of feeding behavior, energy homeostasis and also in regulating cardiovascular system. Variations in the NPY2 receptor genes have been linked to occurrence of Diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Neuropeptide Y receptor type 2; NPY-Y2 receptor; NPY2-R; Y2 receptor
Gene Aliases: NPY2-R; NPY2R
UniProt ID: (Human) P49146
Entrez Gene ID: (Human) 4887
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.