|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 274 and 501 of Human Nicotinic Acetylcholine Receptor beta|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29991 targets Nicotinic Acetylcholine Receptor beta in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29991 immunogen is recombinant fragment corresponding to a region within amino acids 274 and 501 of Human Nicotinic Acetylcholine Receptor beta.
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acetylcholine receptor; Acetylcholine receptor subunit beta; acetylcholine receptor, nicotinic, beta 1 (muscle); ACHRB; beta 1 (muscle); beta polypeptide 1 (muscle); cholinergic receptor; cholinergic receptor, nicotinic beta 1; cholinergic receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); CHRNB; CMS1D; CMS2A; nicotinic; SCCMS
Gene Aliases: ACHRB; CHRNB; CHRNB1; CMS1D; CMS2A; CMS2C; SCCMS
UniProt ID: (Human) P11230
Entrez Gene ID: (Human) 1140
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.