|Western Blot (WB)||1:500|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide: P(125) E L Q T L T R P G A L R A P R R(141)|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-4514 detects splice variants Nop30/ARC of the nucleolar protein Nop30 in human samples.
PA1-4514 has been used successfully in Western blot procedures. By Western blot this antibody detects a ~25 kDa protein representing recombinant Nop30.
The PA1-4514 immunogen corresponds to amino acid residues 125-141 of the 25 kDa human Nop30/ARC protein.
A CARD domain containing protein, designated ARC for apoptosis repressor with CARD, suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The predominant nucleolar localization of the isoform Nop30 points to a potential role in RNA processing in muscle nucleoli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apoptosis repressor with CARD; Muscle enriched cytoplasmic protein; Muscle-enriched cytoplasmic protein; Myp; Nop30; Nucleolar protein 3; nucleolar protein 3 (apoptosis repressor with CARD domain); Nucleolar protein of 30 kDa
Gene Aliases: ARC; FCM; MYP; NOL3; NOP; NOP30
UniProt ID: (Human) O60936
Entrez Gene ID: (Human) 8996
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