|Immunohistochemistry (Paraffin) (IHC (P))||3 - 7 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from near C-terminus of human NR4A3.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Dog, Bat, Elephant, Panda (100%) Marmoset, Rat, Bovine, Hamster, Rabbit, Pig (95%) Mouse (90%).
NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3' variant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CHN; chondrosarcoma, extraskeletal myxoid, fused to EWS; CSMF; MINOR; Mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor; Neuron-derived orphan receptor 1; Nor-1; NR4A3; Nuclear hormone receptor NOR-1; Nuclear receptor subfamily 4 group A member 3; nuclear receptor subfamily 4, group A, member 3; Orphan receptor nor1; TEC receptor; translocated in extraskeletal chondrosarcoma
Gene Aliases: CHN; CSMF; MINOR; NOR1; NR4A3; TEC
UniProt ID: (Human) Q92570
Entrez Gene ID: (Human) 8013
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