|Immunohistochemistry (Paraffin) (IHC (P))||2-4ug/ml|
|Western Blot (WB)||0.2-1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ELHKILLEKKDA) corresponding to the C-terminus amino acids of NUP50|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 50 kDa nucleoporin; CTA-268H5.7; DKFZP564A043; MGC39961; NPAP60; NPAP60L; Nuclear pore complex protein Nup50; Nuclear pore-associated protein 60 kDa-like; nuclear pore-associated protein 60L; nucleoporin 50kD; nucleoporin 50kDa; Nucleoporin Nup50; NUP50; OTTHUMP00000199530
Gene Aliases: NPAP60; NPAP60L; NUP50; PRO1146
UniProt ID: (Human) Q9UKX7
Entrez Gene ID: (Human) 10762
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