|ELISA (ELISA)||Assay Dependent|
|Immunocytochemistry (ICC)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Immunofluorescence (IF)||See 1 publications below|
|Immunoprecipitation (IP)||See 1 publications below|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Full-length recombinant human Nuf2 protein|
|Storage buffer||tissue culture supernatant|
|Contains||0.1% sodium azide|
Nuf2 (also known as CDCA1 or cell division cycle associated 1) is important for the formation of stable kinetochore-microtubule attachments, chromosome alignment in mitosis, and mitotic progression. Nuf2 is a spindle pole body-associated protein required for nuclear division, spindle pole body separation, and spindle elongation. Nuf2 is part of the Ndc80 complex, which is also comprised of Ndc80 (Hec1), Spc24, and Spc25. The Ndc80 complex is essential for metaphase chromosome alignment and anaphase chromosome segregation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cancer/testis antigen 106; CDCA1; cell division cycle associated 1; Cell division cycle-associated protein 1; CT106; hNuf2; hNuf2R; hsNuf2; Kinetochore protein Nuf2; NUF2, NDC80 kinetochore complex component, homolog; NUF2R
Gene Aliases: CDCA1; CT106; NUF2; NUF2R
UniProt ID: (Human) Q9BZD4
Entrez Gene ID: (Human) 83540
Molecular Function: structural protein
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