|Immunohistochemistry (Paraffin) (IHC (P))||4 - 38 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 17 amino acid peptide from N-terminal extracellular domain of human Delta Opioid Receptor.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Gorilla (100%) Human, Monkey, Marmoset, Elephant, Rabbit (94%).
OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimers patients and in the putamen in Parkinsons disease.
Protein Aliases: D-OR-1; delta 1; Delta opiate receptor; Delta opioid receptor; Delta opioid receptor 1; Delta-1 opioid receptor; Delta-type opioid receptor; DOR-1; Opioid delta receptor; Opioid receptor; opioid receptor, delta 1; OPRD; OPRD1
Gene Aliases: OPRD; OPRD1
UniProt ID: (Human) P41143
Entrez Gene ID: (Human) 4985