|Western Blot (WB)||1-2 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (YFERNFSDCPDIY) corresponding to the C-terminus amino acids of OSBPL2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse and rat based on sequence homology.
This gene encodes a member of the oxysterol-binding protein family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
Protein Aliases: FLJ20223; KIAA0772; MGC4307; MGC8342; ORP-2; ORP2; OSBP-related protein 2; OSBPL2; oxysterol binding protein-like 2; oxysterol-binding protein-like protein 2; Oxysterol-binding protein-related protein 2
Gene Aliases: DFNA67; DNFA67; KIAA0772; ORP-2; ORP2; OSBPL2
UniProt ID: (Human) Q9H1P3
Entrez Gene ID: (Human) 9885