|Western Blot (WB)||1-2 µg/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Peptide with sequence YFERNFSDCPDIY, from C Terminus of the protein sequence according to NP_055650; NP_653081|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-32067 detects OSBPL2 from human samples.
PA1-32067 has been successfully used in ELISA and Western blot applications.
The PA1-32067 immunogen is: Peptide with sequence YFERNFSDCPDIY, from C Terminus of the protein sequence according to NP_055650; NP_653081
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
Protein Aliases: FLJ20223; KIAA0772; MGC4307; MGC8342; ORP-2; ORP2; OSBP-related protein 2; oxysterol binding protein-like 2; oxysterol-binding protein-like 2; Oxysterol-binding protein-related protein 2
Gene Aliases: C130070J12Rik; DFNA67; DNFA67; KIAA0772; mKIAA0772; ORP-2; ORP2; OSBPL2