|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Human peptide (amino acid positions 2031) coupled to KLH|
|Storage buffer||whole serum|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-5858 detects OVCA1 in human samples.
PA1-5858 has been successfully used in Western blot procedures.
The PA1-5858 immunogen is human peptide (amino acid positions 2031) coupled to KLH.
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; candidate tumor suppressor in ovarian cancer 1; Diphthamide biosynthesis protein 1; diphthamide biosynthesis protein 2 homolog-like 1; Diphtheria toxin resistance protein 1; diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1; diptheria toxin resistance protein required for diphthamide biosynthesis-like 1; DPH-like 1; DPH1; DPH1 homolog; DPH2-like 1; DPH2L; DPH2L1; FLJ33211; Ovarian cancer-associated gene 1 protein; ovarian tumor suppressor candidate 1; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1
Gene Aliases: DEDSSH; DPH1; DPH2L; DPH2L1; OVCA1
UniProt ID: (Human) Q9BZG8
Entrez Gene ID: (Human) 1801
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