|Flow Cytometry (Flow)||1 µg/10^6 cells|
|Tested Species reactivity||Mouse|
|Host / Isotype||Armenian hamster / IgG, kappa|
|Contains||0.1% sodium azide|
|Storage conditions||4° C|
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD103; Dendritic cells; Integrin alpha M290; Integrin alpha-E; Intregrin alpha E2; ITGAE
Gene Aliases: A530055J10; alpha-E1; alpha-M290; aM290; CD103; Itgae
UniProt ID: (Mouse) Q60677
Entrez Gene ID: (Mouse) 16407
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