|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids P(2) L P D C C R Q K T C S C(14) of human orexin A conjugated to KLH.|
|Storage buffer||PBS, pH 7.2|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
Predicted to react with bovine, chimpanzee, dog, horse, mouse, pig, rabbit, rat and rhesus monkey based on sequence homology.
Hypothalamus tissue can be used as a positive control.
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Hcrt; Hypocretin; hypocretin (orexin) neuropeptide; NRCLP1; Orexin; OX; PPOX; prepro-orexin
Gene Aliases: HCRT; NRCLP1; OX; PPORX; PPOX
UniProt ID: (Human) O43612
Entrez Gene ID: (Human) 3060
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