|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (IHC)||See 1 publications below|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||A synthetic hexadecapeptide (KPDEKYYSSSIWGPTC) (aa345-360) from rat ODC|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-13485 targets Ornithine Decarboxylase in IHC (F) applications and shows reactivity with Human, mouse, and Rat samples.
The MA5-13485 immunogen is a synthetic hexadecapeptide (KPDEKYYSSSIWGPTC) (aa345-360) from rat ODC.
ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Antizyme inhibitor 1; AZI; ODC antizyme inhibitor; ornithine decarboxylase 1-like; Ornithine decarboxylase antizyme inhibitor
Gene Aliases: 1700085L02Rik; AZI; AZIA1; AZIN1; OAZI; OAZIN; ODC1L
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