|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Immunohistochemistry (IHC)||See 2 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Immunohistochemistry (Paraffin, Frozen) (IHC (P, F))||See 1 publications below|
|Tested Species reactivity||Bovine, Human|
|Published species reactivity||Dog , Rat|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||mouse myeloma cell-line P3U1 with spleen cells of BALB/c mouse after immunization with bovine Osteocalcin|
|Purification||Ammonium sulfate precipitation, Ion-exchange chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Storage conditions||4° C|
Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblast that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increase bone turnover such as osteoporosis, hyperparathyroidism, and Paget's disease, and low condition asssociated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BGLAP; BGP; bone gamma-carboxyglutamate (gla) protein (osteocalcin); Bone Gla protein; Gamma-carboxyglutamic acid-containing protein; Osteocalcin
Gene Aliases: BGLAP; BGP; BOS_2768; OC; OCN
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