|Flow Cytometry (Flow)||2 ug/test|
|Western Blot (WB)||1:10-1:200|
|Immunocytochemistry (ICC)||See 4 publications below|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Western Blot (WB)||See 8 publications below|
|Tested Species reactivity||Hamster, Human|
|Published species reactivity||Rat , Human Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human and hamster drug-resistant viable cells followed by crude plasma membranes|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-13854 targets p170 in FACS, WB and ICC/IF applications and shows reactivity with Hamster and Human samples. This antibody does not react with mouse tissue in Western blot applications.
The MA5-13854 immunogen is human and hamster drug-resistant viable cells followed by crude plasma membranes.
Multi-drug resistance(MDR) associated p-glycoprotein (p170) causes resistance to various drugs in a number of cancer patients. It exists in a soluble and membrane associated form. Soluble P-glycoprotein is detected in extracellular fluids of cancer patients, such as malignant ascites and serum. The Mr of soluble P-glycoprotein is the same as that of membrane bound P-glycoprotein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABC20; ATP-binding cassette sub-family B member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; CD243; CLCS; colchicin sensitivity; doxorubicin resistance; GP170; MDR1; Multidrug resistance protein 1; P-glycoprotein 1; P-GP; PGY1
Gene Aliases: ABC20; ABCB1; CD243; CLCS; GP170; MDR1; P-GP; PGY1
UniProt ID: (Human) P08183
Entrez Gene ID: (Human) 5243
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