|Immunofluorescence (IF)||2-10 ug/ml|
|Western Blot (WB)||1-3 ug/ml|
|Miscellaneous PubMed (MISC)||See 2 publications below|
|Western Blot (WB)||See 4 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Tested Species reactivity||Dog, Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human P-Cadherin fusion protein.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
32-4000 has successfully been used in western blot to detect P-cadherin in MDCK cell lysates.
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cadherin 3, type 1, P-cadherin (placental); Cadherin-3; calcium-dependent adhesion protein; calcium-dependent adhesion protein, placental; CDHP; HJMD; P-cadherin; PCAD; placental; Placental cadherin
Gene Aliases: CDH3; CDHP; HJMD; PCAD
UniProt ID: (Human) P22223
Entrez Gene ID: (Human) 1001
Molecular Function: cadherin
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