|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 310 and 374 of Human P2Y11|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28772 targets P2Y11 in WB applications and shows reactivity with Human samples.
The PA5-28772 immunogen is synthetic peptide corresponding to a region within amino acids 310 and 374 of Human P2Y11.
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.
Protein Aliases: P2Y purinoceptor 11; P2Y11; purinergic receptor P2Y, G-protein coupled, 11; purinergic receptor P2Y11
Gene Aliases: P2RY11; P2Y11
UniProt ID: (Human) Q96G91
Entrez Gene ID: (Human) 5032