|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 148 and 364 of Human p38beta|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29302 targets p38beta in WB applications and shows reactivity with Human samples.
The PA5-29302 immunogen is recombinant fragment corresponding to a region within amino acids 148 and 364 of Human p38beta.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAP kinase 11; MAP kinase p38 beta; MAPK 11; Mitogen-activated protein kinase 11; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B; stress-activated protein kina; stress-activated protein kinase 2; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b
Gene Aliases: MAPK11; p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B
UniProt ID: (Human) Q15759
Entrez Gene ID: (Human) 5600
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