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A suggested positive control is human brain tissue lysate.
PA5-21172 can be used with blocking peptide PEP-1286.
Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.
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Protein Aliases: Claudin-like protein 24; claudin-like protein of 24 kDa; Transmembrane protein 204
Gene Aliases: C16orf30; CLP24; TMEM204; UNQ6509/PRO21434
UniProt ID: (Human) Q9BSN7, (Rat) Q5M962, (Mouse) Q7TQI0
Entrez Gene ID: (Human) 79652, (Rat) 287129, (Mouse) 407831
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