|Immunohistochemistry (Paraffin) (IHC (P))||1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Bovine, Human, Mouse, Non-human primate, Rat, Xenopus, Zebrafish|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids at the amino-terminus of human PABP1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
It is not recommended to aliquot this antibody.
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytoplasmic poly(A)-binding protein 1-A; PABP 1; PABP 1-A; PABP-1; PABP-1-A; PABP-A; poly A binding protein 1; poly A binding protein, cytoplasmic 1 a; poly(A) binding protein, cytoplasmic 1; poly(A) binding protein, cytoplasmic 2; poly(A)-binding protein 1; poly(A)-binding protein 1-A; Polyadenylate-binding protein 1; Polyadenylate-binding protein 1-A; xPABP1-A
Gene Aliases: BOS_14049; ePAB; PAB1; PABP; PABP1; PABPC1; pabpc1-a; PABPC2; PabpI; PABPL1; wu:fb16a02; wu:fi19b08; wu:fj12d09; wu:fj61f06; zgc:109879
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