|ELISA (ELISA)||Assay Dependent|
|Flow Cytometry (Flow)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Blocking Assay (BLOCK)||See 3 publications below|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Flow Cytometry (Flow)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Non-human primate , Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||A synthetic peptide corresponding to the N-terminal region of the human thrombin receptor PAR1.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
Thrombin is a serine protease that is involved in platelet aggregation and blood coagulation. It is cleaved from its precursor, prothrombin, and converts fibrinogen to fibrin in the final step of the clotting cascade. Thrombin mediates its regulatory effects by activating cell surface G-protein coupled receptors which include PAR-1, PAR-2 and PAR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CF2R; coagulation factor II (thrombin) receptor; Coagulation factor II receptor; F2R; HTR; PAR-1; PAR1; protease activated receptor 1; Protease-activated receptor 1; Proteinase-activated receptor 1; Thrombin receptor
Gene Aliases: CF2R; F2R; HTR; PAR-1; PAR1; TR
UniProt ID: (Human) P25116
Entrez Gene ID: (Human) 2149
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