|Immunoprecipitation (IP)||2 ug|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||1208-1393 of 1801 of PARP14 Protein.|
|Contains||0.09% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Poly [ADP-ribose] polymerase 14 (PARP14) is a B aggressive lymphoma protein belonging to the PARP protein family. Poly ADP ribosylation is a DNA damage dependent post translational modification of histones and other nuclear proteins that mediates DNA repair. PARP proteins with a macrodomain are also involved in gene expression through transcriptional regulation. PARP14 controls STAT6 dependent transcription by enhancing binding to the promoter in the presence of a positive signal (i.e. IL4 stimulation).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADP-ribosyltransferase diphtheria toxin-like 8; ARTD8; B aggressive lymphoma protein 2; B-aggressive lymphoma 2; BAL2; collaborator of STAT6; KIAA1268; PARP-14; Poly [ADP-ribose] polymerase 14
Gene Aliases: ARTD8; BAL2; KIAA1268; PARP-14; PARP14; pART8
UniProt ID: (Human) B4E2H0
Entrez Gene ID: (Human) 54625
Molecular Function: nucleic acid binding
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