|Western Blot (WB)||0.3-1.0ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (TTLAGAVPRMM) corresponding to the N-terminus amino acids of PAX3|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
This gene is a member of the paired box family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t, which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDHS; HUP2; MGC120381; MGC120382; MGC120383; MGC120384; MGC134778; paired box 3; paired box gene 3 (Waardenburg syndrome 1); paired box homeotic gene 3; paired box homeotic gene 3 (Waardenburg syndrome 1); Paired box protein Pax-3; paired domain gene 3; paired domain gene HuP2; PAX3; WS1
Gene Aliases: CDHS; HUP2; PAX3; WS1; WS3
UniProt ID: (Human) P23760
Entrez Gene ID: (Human) 5077
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