|Western Blot (WB)||0.3-1 ug/ml|
|Tested Species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (REEKLRNQRRQASN) corresponding to the internal amino acids of PAX6|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with human and rat based on sequence homology.
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene.
Protein Aliases: AN; AN2; D11S812E; Dickie's small eye; MGC17209; MGDA; Oculorhombin; paired box gene 6; paired box gene 6 (aniridia, keratitis); paired box homeotic gene 6 (aniridia, keratitis); paired box homeotic gene-6; Paired box protein Pax-6; PAX6; small eye; WAGR
Gene Aliases: 1500038E17Rik; AEY11; Dey; Gsfaey11; Pax-6; Pax6; Sey
UniProt ID: (Mouse) P63015
Entrez Gene ID: (Mouse) 18508