|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 342 and 539 of Human PCCase beta|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30118 targets PCCase beta in WB applications and shows reactivity with Human samples.
The PA5-30118 immunogen is recombinant fragment corresponding to a region within amino acids 342 and 539 of Human PCCase beta.
The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: beta polypeptide; mitochondrial; PCCase subunit beta; Propanoyl-CoA:carbon dioxide ligase subunit beta; propionyl CoA carboxylase, beta polypeptide; propionyl Coenzyme A carboxylase; propionyl Coenzyme A carboxylase, beta polypeptide; propionyl-CoA carboxylase beta chain; Propionyl-CoA carboxylase beta chain, mitochondrial
Gene Aliases: PCCB
UniProt ID: (Human) P05166
Entrez Gene ID: (Human) 5096
Molecular Function: ligase
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