|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human PCDH-Y|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
This gene belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. This gene is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PCDH-Y; PCDH11; PCDH22; PCDHY; protocadherin 22; Protocadherin on the Y chromosome; Protocadherin prostate cancer; Protocadherin-11; Protocadherin-11 Y-linked; Protocadherin-22; Protocadherin-PC
Gene Aliases: PCDH-PC; PCDH11; PCDH11Y; PCDH22; PCDHX; PCDHY
UniProt ID: (Human) Q9BZA8
Entrez Gene ID: (Human) 83259
Molecular Function: cadherin
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