|Western Blot (WB)||0.1-0.5 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (PRYRADEYQPPD) corresponding to the internal amino acids of PCSK9|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: convertase subtilisin/kexin type 9 preproprotein; FH3; HCHOLA3; hypercholesterolemia, autosomal dominant 3; NARC-1; NARC1; neural apoptosis regulated convertase 1; Neural apoptosis-regulated convertase 1; PC9; PCSK9; Proprotein convertase 9; Proprotein convertase subtilisin/kexin type 9; Subtilisin/kexin-like protease PC9
Gene Aliases: FH3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9; PCSK9; PSEC0052
UniProt ID: (Human) Q8NBP7
Entrez Gene ID: (Human) 255738
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